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- Schmerzhaftes Brennen / Jucken in Händen und Füßen – dies scheint das Hauptsymptom zu sein
- Nachts oft schlimmer und / oder bei Hitze oder Kälte noch schlimmer – oft können die Leute die Bettlaken nicht mit ihren Füßen berühren.
- Alkohol kann dieses Symptom ebenfalls verstärken
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- Trockene Augen / Mund
- Anormales Schwitzen
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