Was ist kleine Faser-Neuropathie? Warum ist dies für Fibromyalgie notwendig?

Herzlich willkommen! Es sieht so aus, als wären Sie vielleicht neu hier, deshalb wollte ich Ihnen etwas über mich und meinen Blog erzählen. Ich heiße Julie Ryan und lebe mit Fibromyalgie zusammen. Ich habe mich entschieden, positiv zu leben, mich mit Änderungen der Ernährung und des Lebensstils zu wehren und es hat einen großen Unterschied für mich gemacht. Der Unterschied zwischen leben alle meine Tage im Bett, und tatsächlich  LIVING . Ich hoffe, Sie lesen weiter – sehen Sie in der Seitenleiste nach einer Liste der Lieblingsbeiträge meiner Leser und ..

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In den letzten Jahren haben wir viele Artikel über die Überlappung der kleinen Faser-Neuropathie (oder der kleinen Faser-Polyneuropathie – das gleiche) in Fibromyalgie gesehen und die Hoffnung, dass wir Hautbiopsien dieser kleinen Fasernerven zur Diagnose von Fibromyalgie verwenden können. Ich werde ehrlich sein, dachte ich für eine Weile, als wir gerade die gleiche Studie in den Nachrichten wieder auftauchen sahen (und es hat mich frustriert); Ich habe jedoch gemerkt, dass ich falsch lag. Es gibt tatsächlich einige Studien in so vielen Jahren, die diese Verbindung hergestellt haben. Das heißt, alle Studien, die ich gelesen habe, waren sehr klein (weniger als 30 Teilnehmer), und sie stellen nicht fest, dass alle Fibromyalgie-Patienten dies haben (nur etwa 50% der Studien). Diese Studien sind jedoch möglicherweise ein Sprungbrett, um eine mögliche Ursache für die mit Fibromyalgie verbundenen Schmerzen aufzudecken.

Was ist aber die Small Fiber Neuropathie?

Die Small Fiber Polyneuropathy (SFPN) ist eine Erkrankung (ja, eine tatsächliche Erkrankung), die eine Degeneration in den kleinen Faser-Neuronen verursacht. Die kleinen Faser-Nerven übertragen die Informationen über Schmerz und Temperatur. Diese kleinen Fasern sind auch in vielen Bereichen des autonomen Nervensystems (dem Teil, der die automatischen Funktionen wie Atmen, Verdauung und Blutfluss steuert) beteiligt. Es ist also etwas mehr als nur Brennen und Jucken in den Füßen.

Im Gegensatz zu Problemen in den großen Nerven zeigen sich bei EMG- und Nervenleitungsstudien kleine Faser-Neuropathien nicht. SFPN ist am häufigsten mit Diabetes assoziiert, kann jedoch durch eine Vielzahl anderer Krankheiten und Krankheiten verursacht werden und sogar genetisch bedingt sein. Eine Hautbiopsie ist der primäre Weg zur Diagnose von SFPN. Leider ist die Diagnose von SFPN für diejenigen unter uns, die an Fibromyalgie leiden, nicht viel, außer vielleicht haben wir das Gefühl, dass wir eine bessere Diagnose haben als nur Fibromyalgie. Die Behandlungen für SFPN sind im Wesentlichen die gleichen, die wir bereits für Fibromyalgie anwenden (Antidepressiva, Antikonvulsiva, topische Schmerzbehandlungen, Gabapentin und Tramadol, um nur einige zu nennen.

Was sind die Symptome der Small Fiber Neuropathie?
  • Schmerzhaftes Brennen / Jucken in Händen und Füßen – dies scheint das Hauptsymptom zu sein
    • Nachts oft schlimmer und / oder bei Hitze oder Kälte noch schlimmer – oft können die Leute die Bettlaken nicht mit ihren Füßen berühren.
    • Alkohol kann dieses Symptom ebenfalls verstärken
  • Verdauungssymptome einschließlich Durchfall, Verstopfung, Übelkeit, Erbrechen
  • Harninkontinenz
  • Perioden erhöhten Herzschlags
  • Trockene Augen / Mund
  • Anormales Schwitzen
  • orthostatische Hypotonie
  • erektile Dysfunktion
  • Hautveränderungen in den betroffenen Bereichen

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