La science du cannabis développe des patchs pour la douleur chez les patients atteints de fibromyalgie

Cannabis Science, une société spécialisée dans le développement de thérapies à base de cannabis, a récemment annoncé le développement de deux nouveaux médicaments pour le soulagement de la douleur chez les personnes souffrant de fibromyalgie et de neuropathie diabétique avec douleur nerveuse.

Les deux nouveaux analgésiques pharmaceutiques seront commercialisés sous la forme de timbres adhésifs transdermiques qui délivrent une certaine dose de médicament dans la circulation sanguine par absorption à travers la peau du patient.

Les voies d’administration transdermique du médicament ont le potentiel de favoriser la cicatrisation d’une zone lésée du corps. Cette méthode d’administration peut être supérieure à d’autres types d’administration de médicament, y compris orale, topique, intraveineuse, intramusculaire et autres, en raison d’un contrôle supplémentaire sur la dose administrée au patient.

Le patch permet une libération plus contrôlée du médicament, soit en utilisant une membrane poreuse pour permettre l’absorption progressive du médicament à travers la peau, soit en incorporant de fines couches du médicament dans l’adhésif qui fond avec la chaleur corporelle du patient.

Les cannabinoïdes ont un large éventail d’applications médicinales, datant de milliers d’années. Actuellement, plusieurs publications scientifiques examinées par des pairs documentent les voies biochimiques sous-jacentes qui modulent les cannabinoïdes.

Ces patchs contiennent un extrait de cannabinoïde de haute activité (CBD), le deuxième cannabinoïde majeur dans la marijuana après le THC (tétrahydrocannabinol). L’extrait pénètre lentement dans la circulation sanguine, puis pénètre dans le système nerveux central du patient pour agir comme analgésique.

Le CBD a des propriétés anti-inflammatoires et analgésiques sans effets psychoactifs connus. La recherche a montré que le CBD peut être un traitement efficace pour de nombreux types de douleur, en particulier la douleur inflammatoire. Certaines études ont également montré que le CBD peut surpasser les médicaments traditionnels dans le traitement de la douleur inflammatoire.

“Alors que nous nous efforçons d’augmenter la capacité de croissance de nos terres et de produire notre propre produit pour fournir à nos scientifiques des matériaux brevetés pour fabriquer ces formulations, nous sommes également occupés à étudier les besoins potentiels pour des applications médicales liées au cannabis. délivrer ces médicaments », a déclaré Raymond C. Dabney, PDG de Cannabis Science dans un communiqué de presse.

«Comme de plus en plus d’États à l’échelle nationale [aux États-Unis] Légiférer pour la légalisation du cannabis et des drogues dérivées du cannabis, chez Cannabis Science, nous nous concentrons sur le développement de formulations et d’applications pharmaceutiques pour répondre à la demande croissante. années “, a déclaré Dabney.

On estime que la fibromyalgie affecte 2% -8% de la population. Les patients atteints de fibromyalgie éprouvent une douleur chronique généralisée et une plus grande réponse à la douleur sous pression.

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