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Cannabis Science, una compañía especializada en el desarrollo de terapias basadas en el cannabis, anunció recientemente el desarrollo de dos nuevos medicamentos para el alivio del dolor en personas con fibromialgia y neuropatía diabética con dolor nervioso.
Los dos nuevos analgésicos farmacéuticos se comercializarán como parches transdérmicos adhesivos que entregan una cierta dosis de medicamento en el torrente sanguíneo por absorción a través de la piel del paciente.
Las rutas de administración transdérmica de fármacos tienen el potencial de promover la curación de una zona lesionada del cuerpo. Este método de administración puede ser superior a otros tipos de administración de medicamentos, incluso oral, tópico, intravenoso, intramuscular y otros, debido al control adicional sobre la dosis administrada al paciente.
El parche proporciona una liberación más controlada del medicamento, ya sea mediante el uso de una membrana porosa para permitir que el medicamento sea absorbido gradualmente por la piel, o mediante la incorporación de capas delgadas del medicamento en el adhesivo que se derriten con el calor corporal del paciente.
Los cannabinoides tienen un amplio registro de aplicaciones medicinales, que se remonta a miles de años. Actualmente, varias publicaciones científicas revisadas por pares están documentando las rutas bioquímicas subyacentes que modulan los cannabinoides.
Estos parches contienen extracto de cannabinoides de alta potencia (CBD), el segundo cannabinoide principal en la marihuana después del THC (tetrahidrocannabinol). El extracto ingresa lentamente en el torrente sanguíneo y luego penetra en el sistema nervioso central del paciente para actuar como analgésico.
El CBD tiene propiedades antiinflamatorias y analgésicas sin efectos psicoactivos conocidos. La investigación ha demostrado que el CBD puede ser un tratamiento efectivo para muchos tipos de dolor, particularmente dolor inflamatorio. Algunos estudios también han demostrado que el CBD puede superar a la medicación tradicional cuando se trata el dolor inflamatorio.
“Si bien nos esforzamos por aumentar la capacidad de nuestra tierra para el crecimiento y las instalaciones para producir nuestro propio producto para suministrar a nuestros científicos materiales patentados para hacer estas formulaciones, también estamos ocupados investigando más necesidades potenciales de aplicaciones médicas relacionadas con Cannabis y desarrollando los métodos para la entrega de estos medicamentos “, dijo Raymond C. Dabney, CEO de Cannabis Science en un comunicado de prensa.
“A medida que más estados a nivel nacional [en los EE. UU.] Legislan para la legalización del cannabis y los medicamentos derivados del cannabis, aquí en Cannabis Science estamos enfocados en desarrollar formulaciones y aplicaciones farmacéuticas para abastecer la enorme demanda creciente que se espera en los próximos años”, Dabney fijado.
Se estima que la fibromialgia afecta al 2% -8% de la población. Los pacientes con fibromialgia experimentan dolor crónico generalizado y una mayor respuesta al dolor ante la presión.
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