Kliniske forskningsresultater: Fibromyalgi relatert til hysterektomi, gynekologisk sykdom: Også relatert til endokrine og autoimmune sykdommer

Har du gjennomgått en gynekologisk kirurgi, for eksempel en hysterektomi, noen år før oppstart av fibromyalgi?

Noen mennesker har lagt merke til denne trenden, og en studie publisert i 2015 etablerer sammenhengen mellom disse typer operasjoner og utseendet av fibromyalgi. Det gir også ytterligere bevis på en sammenheng mellom fibromyalgi og overlappende, gynekologisk, endokrine eller autoimmune forhold.

resultater

Som en del av studien undersøkte forskerne opptakene av 219 kvinner med fibromyalgi og 116 kvinner med kronisk smerte annet enn fibromyalgi. Nærmere bestemt undersøkte de tiden som gikk mellom sykdomsutbrudd og gynekologisk kirurgi, samt antall overlappende sykdommer i hver gruppe.

De fant også at hver av de tre typer diagnose som ble studert, var uavhengig forbundet med fibromyalgi. Skjoldbrusk sykdom og gynekologisk kirurgi var betydelig mer vanlig hos kvinner med fibromyalgi enn hos de med andre typer kronisk smerte.

Tidspunktet for gynekologiske operasjoner i forhold til smertestart var spesielt interessant. De fant flere operasjoner i årene før oppstått av fibromyalgi-relatert smerte eller året etter smertestart. Denne modellen var unik for gruppen fibromyalgi.

Ved første øyekast kan det virke rart at gynekologiske operasjoner utført i året etter smertestart anses å være relatert til utviklingen av fibromyalgi.

En slik forening kan imidlertid skyldes flere relevante faktorer.

Tenk for eksempel at mange kvinner har gynekologiske problemer lenge før de velger operasjon som behandling av valg. Hormonale endringer eller gynekologiske sykdommer kan være risikofaktorer for fibromyalgi på grunn av et underliggende forhold som vi ennå ikke forstår.

Ifølge studien var hysterektomi og ovariektomi (fjerning av eggstokkene) mest sannsynlig i de fire årene før eller etter begynnelsen av fibromyalgi smerte.

Dette er absolutt et område som krever mer forskning. Til slutt kan dette hjelpe oss med å forstå hvorfor 90% av fibromyalgipatienter er kvinner. Utover det kan det avsløre fysiologiske endringer som kan utløse utviklingen av sykdommen, noe som kan føre til bedre behandlinger eller til og med forebygging.

For kvinner som utvikler Fibromyalgi etter gynekologisk kirurgi, vi trenger også å vite hvilken rolle, om noen, operasjonen selv og den mulige rollen til hormonelle endringer forårsaket av kirurgi. Den post-kirurgi hormonbehandling er også verdt en titt.

Forrige søk

Leger har lenge mistanke om at fibromyalgi har sterke hormonelle koblinger og utløsere. En 2013-studie fant sammen lenker mellom tidlig overgangsalder og økt smertefølsomhet hos pasienter med fibromyalgi, som kan være relatert til lavere østrogennivåer.

Kvinner med fibromyalgi er spesielt utsatt for smertefull menstruasjon (dysmenoré) og noen komplikasjoner av graviditet.

Min erfaring

Denne studien snakker virkelig til min egen erfaring. Jeg var 34 år gammel da mitt yngste barn ble født av keisersnitt og 35 år når jeg stoppet amming. Ifølge min gynekolog, begynte de hormonelle endringene som fulgte meg i en tidlig perimenopause.

Menstruasjonssyklusen min ble uregelmessig og reglene ekstremt tunge og smertefulle, mens de alltid hadde vært vanlige og relativt myke. Fibromyagia symptomer fulgte raskt.

Seks måneder senere, hadde jeg blitt diagnostisert og identifisert et mønster: blussene mine oppstod regelmessig mellom eggløsning og begynnelsen av mine perioder. Min gynekolog har anbefalt fjerning av endometrium for å kvitte seg med hormonene som kasseres ved fortykkelsen av livmoren.

Ablation avsluttet ikke bare de smertefulle periodene (og reglene generelt), men det lindrede også mine anfall og gjorde dem mindre talrige og fjernere fra hverandre. (Lær mer om min personlige kastede kurs: Fibromyalgi går inn i livet mitt.)

Jeg hadde ikke hatt en hysterektomi, men mellom to graviditeter og to keisersnitt, i tillegg til amming, hadde kroppen min tydeligvis gjennomgått en hormonell ring.

Jeg mistenker at forskningen vil fortsette å demonstrere sammenhenger mellom fibromyalgi og hormonelle forandringer, og jeg håper at en dag vil vi være mye bedre rustet til å gjenkjenne, behandle og forebygge hormonelatert fibromyalgi.

185 thoughts on “Kliniske forskningsresultater: Fibromyalgi relatert til hysterektomi, gynekologisk sykdom: Også relatert til endokrine og autoimmune sykdommer

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