La douleur de la fibromyalgie pourrait être facilitée par des injections de la lidocaine anti-douleur, une nouvelle étude suggère.
Les personnes atteintes de fibromyalgie se plaignent de la douleur chronique tout au long de leur corps ainsi qu’une sensibilité accrue à la douleur. Les médecins ont souvent du mal à traiter cette douleur car on ne sait pas quelles sont les causes, les auteurs de l’étude ont noté.
Dans la nouvelle étude, l’injection dans les tissus périphériques lidocaine – tels que les muscles des épaules ou les fesses – sensibilité à la douleur efficacement réduite, les chercheurs ont constaté.
« Nous avons supposé que si la douleur provient des tissus périphériques, et nous pouvons prendre cette douleur loin en injectant des anesthésiques locaux, alors ce serait une preuve indirecte de l’importance des tissus périphériques pour la douleur clinique de ces personnes, » auteur principal de l’étude, le Dr Roland Staud, professeur de médecine à l’Université de Floride College of Medicine, a déclaré dans un communiqué de nouvelles de l’université.
« Over-the-médicaments en vente libre et [narcotique] prescriptions telles que les opiacés ne sont pas vraiment efficaces pour contrôler la douleur chronique », at-il ajouté. Mais avec la nouvelle thérapie, « nous sommes en mesure d’expliquer la douleur des patients chroniques mieux et mieux le gérer », a déclaré Staud. « Nous faisons des progrès, mais cela prendra du temps. »
L’étude a porté sur 62 femmes atteintes de fibromyalgie. Chaque femme a reçu quatre injections: deux dans certains muscles de leurs épaules et deux autres dans leurs fesses. Certaines des femmes ont reçu des injections de lidocaïne, tandis qu’un « groupe témoin » a reçu des injections de solution saline.
Juste avant les injections ont été données et 30 minutes plus tard, les femmes ont reçu des stimulations douces douleur délivrés par des moyens mécaniques ou par la chaleur.
Par rapport aux injections salines « factices », la lidocaine a grandement facilité la sensibilité des femmes à la douleur, selon l’étude publiée récemment dans le European Journal of Pain .
Les chercheurs ont noté, toutefois, que les deux lidocaine et placeboresulted une réduction de 38 pour cent dans la douleur ou à proximité du point de blessure.
Mais la douleur chronique affecte le corps différemment d’une blessure spécifique, comme une jambe cassée, les auteurs de l’étude ont indiqué. La douleur chronique, ils ont expliqué, modifie effectivement la fonction nerveuse le long de la moelle épinière.
« La meilleure façon de traiter la douleur chronique est. . . [Par] regardant émotionnel, les dommages et les tissus sensoriels, » Michael Robinson, directeur de l’Université de Floride Centre de recherche sur la douleur et la santé comportementale, a déclaré dans un communiqué de nouvelles de l’université. « Nous savons qu’il ya des éléments centraux et périphériques et sociaux et comportementaux à quelqu’un en disant:« Aïe, ça fait mal. »
Les survivants du cancer qui éprouvent de la douleur, par exemple, peut l’associer à leur maladie et les craintes au sujet de leur pronostic – même si elle a été traitée et en rémission.
« Cette sensation peut se sentir bien plus douloureux que s’ils ont juste pensé qu’il était un muscle pincé, » Robinson a expliqué.
Deux experts dans la fibromyalgie ne savaient pas au sujet de la signification des résultats, cependant.
« Il n’y avait pas de différence significative entre la réduction de la douleur dans le groupe placebo par rapport au groupe de traitement – cela signifie qu’il n’a pas d’importance ce que le produit d’injection est, mais l’acte d’injection elle-même pourrait être la cause de la réduction de la douleur », a déclaré le Dr Waseem Mir, rhumatologue à l’hôpital Lenox Hill à New York.
« On peut alors soutenir que la réduction de la douleur était un placebo », at-il dit. « Examiner le point placebo, un autre bras dans l’expérience pourrait devoir être introduite lorsque les patients ne reçoivent pas une injection, mais prendre une pilule placebo. »
Le Dr Houman Danesh est directeur de la gestion de la douleur d’intégration à l’hôpital Mount Sinai à New York. Il a dit que « la fibromyalgie est un trouble complexe où les patients sont plus sensibles à la douleur. Il est principalement diagnostiquée par un rhumatologue en touchant 18 points de pression de diagnostic, et si 11 d’entre eux sont sensibles, alors le diagnostic est fait, » at-il expliqué.
« Cette étude offre un aperçu à un contributeur potentiel à la fibromyalgie et un traitement possible », a déclaré Danesh. « Il est intéressant de noter que les points qui ont été utilisés étaient des points d’acupuncture, suggère donc l’acupuncture comme traitement possible pour aider les patients atteints de fibromyalgie. »
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