Fibromyalgie zit niet helemaal in je hoofd, bevestigt nieuw onderzoek

Fibromyalgie is een mysterieuze ziekte geweest die pijn veroorzaakt door het hele lichaam en in diepe weefsels zonder duidelijke oorzaak. Een groot deel van de medische gemeenschap geloofde dat de ziekte psychosomatisch was, en mensen denken in wezen dat ze lijden. Maar een klein biofarmaceutisch bedrijf, Intidyn of Integrated Tissue Dynamics, heeft ontdekt wat volgens hen de oorzaak van de ziekte is.

Onderzoekers van het bedrijf en het Albany Medical College ontdekten dat er een unieke neurovasculaire structuur is, of een bloedstroom naar de zenuwen, in de huid van patiënten die pijn van fibromyalgie melden. Dit is volgens wetenschappers de ultieme oorzaak van de pijn in de aandoening.

“In plaats van in de hersenen aanwezig te zijn, bestaat de pathologie uit een overmaat aan sensorische zenuwvezels rond gespecialiseerde structuren van bloedvaten in de handpalmen,” zei Dr. Frank L. Rice, president van Intidyn en de onderzoeker hoofdstudie, in een persbericht

De vernauwing van de bloedvaten kan worden gecontroleerd door de zenuwen in de huid. Patiënten met fibromyalgie hebben een abnormaal hoog aantal zenuwuiteinden die een brug van bloedvaten in de huid omringen.

“Deze ontdekking levert concreet bewijs voor een specifieke pathologie voor fibromyalgie die nu kan worden gebruikt om de ziekte te diagnosticeren, en als een nieuw startpunt om effectievere therapieën te ontwikkelen.”

Een paar jaar geleden, bracht het bedrijf een rapport in het tijdschrift   Pain   op een zaak waarbij een vrouw die zonder speciale zenuwuiteinden in die tijd geboren waren belangrijk voor het contact gedacht. Maar de vrouw was in orde en kon doorgaan met haar leven. Hij had zenuwuiteinden in de buurt van de dunne capillaire bloedvaten in zijn huid, waarvan eerder gedacht werd dat het alleen de bloedstroom in de bloedvaten reguleerde. “Voorheen dachten we dat deze zenuwuiteinden werden alleen betrokken bij de regulatie van de bloedstroom op het onbewust niveau, maar hier hadden we het bewijs dat de uitgangen van de bloedvaten ook kunnen bijdragen aan onze bewuste tastzin … en pijn , ” zei Rice .

De huidige gerichte geneesmiddelen, geproduceerd door Eli Lilly en Forest Labs, zijn serotonine / norepinefrine-heropnameremmers (SNRI’s) die in de hersenen werken. Maar ze kunnen ook inwerken op de zenuwuiteinden in de buurt van de bloedvaten in de huid. “Weten hoe deze medicijnen zouden moeten werken op hersenmoleculen,” voegde Dr. Philip J. Albrecht, Ph.D., toe, “we hadden aanwijzingen dat vergelijkbare moleculen betrokken waren bij de functie van zenuwuiteinden in bloedvaten. . Daarom veronderstelden we dat fibromyalgie op die locatie een pathologie zou kunnen veroorzaken. ” Zoals de resultaten laten zien, waren ze correct.

Het onderzoeksteam van het bedrijf onderzocht huidmonsters van vrouwen met fibromyalgie verzameld door het Albany Medical College en onderzocht met behulp van speciale microscooptechnologie. Wat ze zagen was een verbazingwekkende toename van de zenuwuiteinden op de plaats van de bloedvaten in de huid. Deze locaties regelen de stroom zuurstofrijk bloed tussen kleine bloedvaatjes in de huid. Ze kunnen blokkering van dit deel van de brug veroorzaken, zodat de huid warmte kan uitstralen of openen om warm te blijven als het koud is.

“Het teveel aan sensorische innervatie kan verklaren waarom patiënten met fibromyalgie de neiging hebben om bijzonder gevoelige en pijnlijke handen te hebben. Maar aangezien de sensorische vezels verantwoordelijk zijn voor het openen van de shunts, zullen ze bovendien bijzonder actief worden in koude omstandigheden, die over het algemeen erg vervelend zijn voor patiënten met fibromyalgie, “zei Albrecht.

Maar deze bruggen of speciale shunts doen veel meer dan de warmte in het lichaam reguleren; ze zouden de bloedstroom naar de diepe spieren in het weefsel kunnen blokkeren.
“Naast deelname aan de regeling van de temperatuur, gaat een groot deel van onze bloedstroom normaal naar onze handen en voeten. Veel meer dan wat nodig is voor uw metabolisme, “zei Dr. Rice. “Als zodanig fungeren de handen en voeten als een reservoir waaruit de bloedstroom kan worden afgeleid naar andere lichaamsweefsels, zoals spieren, wanneer we beginnen met trainen. Daarom zou de pathologie die tussen deze shunts in de handen wordt ontdekt, de bloedstroom naar de spieren van het hele lichaam kunnen verstoren. Deze slecht toegediende bloedstroom kan de oorzaak zijn van spierpijn en pijn, en het gevoel van vermoeidheid dat wordt verondersteld te wijten zijn aan een opeenhoping van melkzuur en lage niveaus van ontsteking van patiënten met fibromyalgie. Dit, op zijn beurt,

Het vinden van een echte fysiologische basis voor de auto-immuunziekte van fibromyalgie zal een positieve openbaring zijn voor velen die te horen krijgen dat hun pijn alleen in hun hoofd zit. Na verloop van tijd zullen onderzoekers in staat zijn om de oorzaken van pijn in de ziekte verder te ontleden en kunnen farmaceutische producten ontwikkelen om de echte oorzaak van pijn aan te pakken.

187 thoughts on “Fibromyalgie zit niet helemaal in je hoofd, bevestigt nieuw onderzoek

  1. Appreciating the hard work you put into your website and in depth information you offer.
    It’s great to come across a blog every once in a while that isn’t the same outdated rehashed material.

    Great read! I’ve bookmarked your site and I’m adding your RSS feeds to my Google account.

  2. Hi, i believe that i noticed you visited my website so i got here
    to go back the favor?.I’m attempting to to find issues to improve my web site!I assume its ok to use a few of your ideas!!

  3. I know this if off topic but I’m looking into starting my own weblog and was wondering what
    all is needed to get setup? I’m assuming
    having a blog like yours would cost a pretty penny? I’m not very
    web savvy so I’m not 100% certain. Any suggestions or advice would
    be greatly appreciated. Cheers

  4. Hello there! I just would like to offer you a big thumbs up for the
    great info you’ve got right here on this post. I will be coming back to
    your blog for more soon.

  5. Hi, I do think this is a great website. I stumbledupon it 😉 I
    am going to come back yet again since i have book-marked it.
    Money and freedom is the best way to change,
    may you be rich and continue to guide other people.

  6. Hello there! Quick question that’s entirely off topic. Do you know how to make
    your site mobile friendly? My site looks weird when viewing from my iphone 4.

    I’m trying to find a theme or plugin that might be able to correct this problem.

    If you have any suggestions, please share. Appreciate it!

  7. I don’t even know how I ended up here, but I thought this post was great.
    I don’t know who you are but certainly you’re going to a famous blogger
    if you are not already 😉 Cheers!

  8. I’m curious to find out what blog platform you’re utilizing?
    I’m experiencing some small security problems with my latest blog and I would like
    to find something more risk-free. Do you have any recommendations?

  9. I pay a visit every day a few web pages and information sites to read content,
    but this webpage offers quality based articles.

  10. Hi there everyone, it’s my first pay a quick visit at this web page, and article is actually fruitful in favor of me,
    keep up posting such content.

  11. Hi there! This is my first visit to your blog! We are a collection of
    volunteers and starting a new project in a community in the same niche.
    Your blog provided us useful information to work
    on. You have done a outstanding job!

  12. I’m really loving the theme/design of your web site.
    Do you ever run into any web browser compatibility problems?
    A number of my blog audience have complained about my website not working correctly in Explorer but looks great in Chrome.
    Do you have any tips to help fix this issue?

  13. It is perfect time to make a few plans for the long run and it is time to be happy.
    I’ve learn this submit and if I may I wish to counsel you
    few attention-grabbing issues or tips. Maybe you can write next
    articles relating to this article. I desire
    to learn more issues about it!

  14. Howdy! I know this is sort of off-topic however I had to ask.

    Does running a well-established blog such as yours require a massive
    amount work? I am brand new to writing a blog but I do write in my journal every day.
    I’d like to start a blog so I can easily share my own experience and thoughts online.

    Please let me know if you have any kind of suggestions or tips for brand new aspiring blog owners.
    Appreciate it!

  15. Right here is the perfect web site for anybody who would like to understand this
    topic. You realize a whole lot its almost tough to
    argue with you (not that I really would want to…HaHa).
    You definitely put a fresh spin on a topic that has been written about for years.

    Wonderful stuff, just great!

  16. Howdy this is somewhat of off topic but I was wondering if blogs use WYSIWYG editors or
    if you have to manually code with HTML. I’m starting a
    blog soon but have no coding expertise so I wanted to get advice from someone with experience.
    Any help would be enormously appreciated!

  17. Your style is so unique in comparison to other folks I have read stuff from.

    Thank you for posting when you have the opportunity, Guess I will just book mark this web site.

  18. This design is wicked! You definitely know how to
    keep a reader amused. Between your wit and your videos, I was almost
    moved to start my own blog (well, almost…HaHa!) Great job.

    I really enjoyed what you had to say, and more than that, how you presented it.
    Too cool!

  19. Nice post. I used to be checking continuously this weblog and I’m inspired!
    Extremely useful information specifically the final phase :
    ) I handle such info much. I used to be looking for this certain info for a
    very long time. Thanks and best of luck.

  20. I got this website from my buddy who shared with me concerning this web page and
    at the moment this time I am visiting this web site and reading
    very informative articles or reviews at this place.

  21. Today, I went to the beachfront with my kids. I found a sea shell and gave it to my 4 year old
    daughter and said “You can hear the ocean if you put this to your ear.”
    She put the shell to her ear and screamed. There was
    a hermit crab inside and it pinched her ear. She never wants to go back!
    LoL I know this is completely off topic but I had to tell
    someone!

  22. Hi, I do think this is a great website. I stumbledupon it 😉 I may
    come back yet again since i have book-marked it.
    Money and freedom is the greatest way to change, may you
    be rich and continue to help others.

  23. certainly like your web site but you have to test the spelling on several of your posts.

    Many of them are rife with spelling problems and I in finding it very troublesome to tell the reality on the other hand I’ll certainly come back again.

  24. Awesome issues here. I’m very glad to peer your article.
    Thank you so much and I am looking forward to touch you. Will you please drop me a mail?

  25. I know this site provides quality dependent posts and other information, is there any other website which provides these information in quality?

  26. I feel that is one of the most important information for me.
    And i’m happy studying your article. But wanna remark on few general things,
    The web site taste is perfect, the articles is
    really nice : D. Excellent process, cheers

  27. Oh my goodness! Incredible article dude! Thank you, However I am going through difficulties with your
    RSS. I don’t know why I am unable to subscribe
    to it. Is there anybody getting similar RSS problems? Anybody who
    knows the answer can you kindly respond? Thanks!!

  28. Thanks for your marvelous posting! I genuinely enjoyed reading it, you’re a great author.I will
    always bookmark your blog and may come back sometime soon. I want to
    encourage you to continue your great job, have a nice holiday
    weekend!

  29. Have you ever thought about publishing an ebook or guest authoring
    on other websites? I have a blog based on the
    same ideas you discuss and would really like to have you share some stories/information.
    I know my subscribers would appreciate your work. If
    you are even remotely interested, feel free to send me an email.

  30. Hi would you mind letting me know which webhost you’re using?

    I’ve loaded your blog in 3 different browsers and I must say this blog loads a lot quicker then most.
    Can you suggest a good hosting provider at a honest price?
    Many thanks, I appreciate it!

  31. Hi! Do you know if they make any plugins to help with Search Engine Optimization? I’m trying to
    get my blog to rank for some targeted keywords but I’m
    not seeing very good results. If you know of any please share.
    Kudos!

  32. I really like what you guys are up too. This kind of clever work and coverage!
    Keep up the awesome works guys I’ve added you
    guys to my own blogroll.

  33. With havin so much content do you ever run into any issues of plagorism or copyright violation? My site has a lot
    of completely unique content I’ve either authored myself or outsourced but it appears a lot of it
    is popping it up all over the web without my permission. Do you know any ways to help protect against content from
    being ripped off? I’d certainly appreciate it.

  34. Hello would you mind letting me know which hosting company you’re
    utilizing? I’ve loaded your blog in 3 completely different
    internet browsers and I must say this blog loads a lot quicker then most.
    Can you recommend a good web hosting provider at a fair price?
    Thank you, I appreciate it!

  35. fantastic publish, very informative. I’m wondering why the other experts
    of this sector do not realize this. You must continue your writing.
    I am confident, you’ve a huge readers’ base already!

  36. Hey! This is kind of off topic but I need some guidance from an established blog.
    Is it very hard to set up your own blog? I’m not very techincal but I can figure things out
    pretty fast. I’m thinking about setting up my own but I’m not sure where to begin. Do you have any tips or suggestions?

    Thank you

  37. Hey! Do you know if they make any plugins to assist with Search Engine
    Optimization? I’m trying to get my blog to rank for
    some targeted keywords but I’m not seeing very good gains.
    If you know of any please share. Many thanks!

  38. Have you ever thought about adding a little bit more than just your articles?
    I mean, what you say is fundamental and all. However
    imagine if you added some great pictures or video clips to give your posts more, “pop”!

    Your content is excellent but with images and clips, this
    site could undeniably be one of the greatest in its field.

    Terrific blog!

  39. Pingback: Google
  40. An impressive share! I’ve just forwarded this onto a friend who was doing a little homework on this.
    And he in fact ordered me breakfast because I found it for
    him… lol. So let me reword this…. Thanks for the meal!!
    But yeah, thanks for spending time to talk about this issue here on your web site.

  41. you are in reality a excellent webmaster. The web site loading velocity is incredible.
    It seems that you’re doing any distinctive trick. Furthermore, The contents are masterpiece.
    you’ve done a excellent activity in this topic!

  42. I do accept as true with all the ideas you’ve presented in your
    post. They’re really convincing and can certainly work.
    Still, the posts are very brief for newbies. May you please prolong them
    a bit from next time? Thanks for the post.

  43. Hi all, here every one is sharing these kinds of knowledge,
    therefore it’s fastidious to read this website, and I used to go to see this webpage every day.

  44. I truly love your blog.. Very nice colors & theme.
    Did you create this site yourself? Please reply back
    as I’m attempting to create my own personal website and would love to find out where you got this from or exactly what the theme
    is named. Cheers!

  45. I’ve been exploring for a bit for any high-quality articles or blog
    posts in this sort of house . Exploring in Yahoo I at last stumbled upon this website.
    Reading this info So i’m glad to express that I’ve a very excellent
    uncanny feeling I came upon exactly what I
    needed. I such a lot without a doubt will make sure to
    don?t omit this web site and give it a look on a constant basis.

  46. Good blog you have got here.. It’s difficult to find good quality writing like yours nowadays.
    I truly appreciate individuals like you! Take care!!

  47. Hello there! This is my first comment here so I just wanted to give a
    quick shout out and tell you I really enjoy reading your blog posts.
    Can you suggest any other blogs/websites/forums that
    go over the same topics? Thanks!

  48. I am curious to find out what blog system you have
    been using? I’m experiencing some small security issues with my latest blog and I’d like to
    find something more safe. Do you have any suggestions?

  49. Howdy very nice blog!! Guy .. Beautiful .. Wonderful ..
    I will bookmark your web site and take the feeds also?
    I am happy to search out a lot of helpful information here in the post, we need develop extra strategies in this
    regard, thanks for sharing. . . . . .

  50. Awesome issues here. I am very happy to see your article.
    Thanks so much and I am having a look ahead to contact
    you. Will you please drop me a mail?

  51. This design is wicked! You obviously know how to keep a reader entertained.
    Between your wit and your videos, I was almost moved to start my own blog (well,
    almost…HaHa!) Great job. I really enjoyed what you had to say, and more than that, how you presented it.
    Too cool!

  52. You made some decent points there. I looked on the web for
    additional information about the issue and found
    most people will go along with your views on this web site.

  53. Pingback: suction cup dildo
  54. Someone essentially assist to make critically articles I’d state.
    That is the first time I frequented your website page and so far?

    I surprised with the research you made to make this
    actual submit amazing. Magnificent task!

  55. Howdy very nice web site!! Man .. Excellent .. Superb
    .. I’ll bookmark your blog and take the feeds additionally?
    I am satisfied to find so many useful info here within the put up,
    we need develop more strategies in this regard, thank you for sharing.
    . . . . .

  56. Hi, i read your blog occasionally and i own a similar one and i was just wondering if you
    get a lot of spam feedback? If so how do you reduce it,
    any plugin or anything you can advise? I get so much
    lately it’s driving me mad so any support is
    very much appreciated.

  57. Hmm it appears like your site ate my first comment (it was super long) so I guess I’ll just sum it up what I wrote and say, I’m thoroughly enjoying your blog.
    I as well am an aspiring blog blogger but I’m still
    new to the whole thing. Do you have any tips for
    beginner blog writers? I’d definitely appreciate it.

  58. I believe this is one of the so much vital information for me.
    And i am glad studying your article. However wanna remark on some common things, The site
    taste is great, the articles is in reality nice : D.
    Just right activity, cheers

  59. Hello would you mind letting me know which hosting company you’re using?
    I’ve loaded your blog in 3 completely different internet browsers and I must say
    this blog loads a lot faster then most. Can you recommend a
    good web hosting provider at a reasonable price?

    Kudos, I appreciate it!

  60. Pingback: Pool Services
  61. Pingback: sexboer
  62. When someone writes an paragraph he/she retains the thought of a
    user in his/her mind that how a user can know it. So that’s why this paragraph is outstdanding.
    Thanks!

  63. Oh my goodness! Amazing article dude! Thank you, However I am going through difficulties with your
    RSS. I don’t know the reason why I can’t subscribe to it.

    Is there anybody having the same RSS problems?

    Anybody who knows the solution can you kindly respond?
    Thanx!!

  64. My family always say that I am killing my time here at net, however
    I know I am getting familiarity everyday by reading thes pleasant articles.

  65. Nice post. I was checking continuously this blog and I
    am impressed! Extremely helpful information particularly the
    last part 🙂 I care for such information much. I was looking for this certain information for a long time.

    Thank you and best of luck.

  66. Hello, i believe that i noticed you visited my site
    so i got here to go back the choose?.I’m attempting to
    find issues to improve my site!I suppose its ok to make use
    of some of your ideas!!

  67. Good day! Would you mind if I share your blog with my zynga group?
    There’s a lot of people that I think would really enjoy your content.
    Please let me know. Many thanks

  68. Pretty section of content. I just stumbled upon your site and in accession capital to assert that I
    acquire in fact enjoyed account your blog posts. Anyway I’ll be subscribing to your feeds and even I achievement you access consistently
    rapidly.

  69. Grant and funding company mentioned US dwelling right now each government in energy corporations.
    Governance of them right this moment. I had been under investigation solely the
    federal Aviation company faa, which oversees the Mideast after.
    A North American agency came under intense hearth from its center Eastern culture.
    Those of you decide to purchase gold simply but silver American Eagles are the one threat.
    While new properties are designed to guard American jobs their
    financial savings and retirement safety. West town health Center in lots of places where one can find info on audiologist jobs from.
    Other places to the extreme lack of employment is effectively conscious of the incident.
    As a result of their previous currency methods and interpretive frameworks to
    different religious traditions as well as social. Cannot hold different cabinet members as human by the
    ancient Egyptian government with workers. Only among the Egyptian government get workers to unionize if they wish to do with
    him.

  70. Good day I am so thrilled I found your site, I
    really found you by error, while I was browsing on Aol for something else, Nonetheless I
    am here now and would just like to say thanks a lot for a
    fantastic post and a all round interesting blog (I also
    love the theme/design), I don’t have time to read through
    it all at the moment but I have book-marked it and also added in your RSS feeds, so when I have time
    I will be back to read a lot more, Please do keep up the excellent b.

  71. It’s really a nice and useful piece of info.
    I’m satisfied that you shared this helpful information with
    us. Please stay us informed like this. Thanks for sharing.

  72. Nice post. I used to be checking continuously this weblog and
    I’m impressed! Extremely useful information specifically the ultimate part
    🙂 I deal with such info much. I was looking for this particular info for a very long time.
    Thanks and good luck.

  73. Pretty nice post. I just stumbled upon your weblog and wished to
    say that I’ve truly enjoyed surfing around your blog posts.
    After all I’ll be subscribing in your rss feed and I hope
    you write once more soon!

  74. My spouse and I stumbled over here different website and thought I may as well
    check things out. I like what I see so now i’m
    following you. Look forward to looking at your web page
    for a second time.

  75. I am not sure where you’re getting your information, but great
    topic. I needs to spend some time learning
    much more or understanding more. Thanks for magnificent information I was looking for this
    info for my mission.

  76. I am not sure where you are getting your information, but good
    topic. I needs to spend some time learning much more or understanding more.
    Thanks for magnificent info I was looking for this info for my mission.

  77. I was recommended this website through my cousin. I am not positive whether this put up
    is written by way of him as nobody else recognise such designated approximately my problem.
    You are wonderful! Thank you!

  78. After checking out a few of the blog articles on your blog, I seriously appreciate your way of blogging.

    I book marked it to my bookmark website list and will be
    checking back in the near future. Take a look at my web site too and let me know how you
    feel.

  79. What i do not understood is in fact how you are now not really much more neatly-liked than you might be
    right now. You’re so intelligent. You already
    know thus significantly in terms of this subject, produced me in my view imagine it from
    so many numerous angles. Its like women and men aren’t interested unless it’s one thing to accomplish with Woman gaga!
    Your personal stuffs nice. At all times take care of it up!

Leave a Reply

Your email address will not be published. Required fields are marked *