Fibromyalgie: eine Entzündung des Gehirns zum ersten Mal gezeigt.

Die generalisierte Entzündung im Gehirn von Patienten mit Fibromyalgie wurde soeben identifiziert. Ein echter Fortschritt in Bezug auf diese wenig bekannte und wenig anerkannte Krankheit.

Zum ersten Mal entdeckten die Forscher eine weit verbreitete Entzündung des Gehirns bei Patienten mit Fibromyalgie  *  , einer wenig bekannten Erkrankung. Was, um neue Therapien zu entwickeln Sein Bericht wurde in der Fachzeitschrift  Brain, Behavior and Immunity veröffentlicht  . “Das Auffinden objektiver neurochemischer Veränderungen im Gehirn von Patienten mit Fibromyalgie sollte dazu beitragen, das anhaltende Stigma, mit dem viele Patienten konfrontiert sind, zu verringern. Ihnen wird oft gesagt, dass ihre Symptome imaginär sind und dass sie nichts haben “, sagt er. Marco Loggia, Forschungsdirektor.

Die Diagnose einer Fibromyalgie ist weiterhin schwer zu stellen

Chronische Schmerzen sind das Hauptsymptom für Fibromyalgie. Andere Symptome (Müdigkeit, Schlafstörungen, Gedächtnisverlust usw.) sind von Patient zu Patient unterschiedlich und ändern sich mit der Zeit. Trotz der Identifizierung dieser klinischen Manifestationen ist die Diagnose von Fibromyalgie weiterhin schwer zu stellen. Bisher konnte keine Laboruntersuchung oder radiologische Untersuchung dies bestätigen. 

Wir analysierten 20 Patienten mit Fibromyalgie und 14 Kontrollpersonen in einem ersten Team. Zur gleichen Zeit hatte eine andere Forschergruppe eine Kohorte von 11 Patienten und einer gleichen Anzahl von Kontrollpersonen gebildet. Die Wissenschaftler verglichen ihre Daten, um gemeinsame Schlussfolgerungen zu ziehen.

Aktivierung von Gliazellen in verschiedenen Regionen des Gehirns.

Letztendlich war die Aktivierung von Gliazellen in mehreren Regionen des Gehirns von Patienten mit Fibromyalgie signifikant höher als bei den Kontrollpersonen. Im Nervensystem sind Gliazellen die Zellen, die die Umgebung von Neuronen bilden. “Die in unseren Studien beobachtete Aktivierung der Gliazellen setzt Entzündungsmediatoren frei, von denen angenommen wird, dass sie die Schmerzwege sensibilisieren und zu Symptomen wie Müdigkeit beitragen”, schließt Marco Loggia. *

Laut der Fibromyalgie France-Vereinigung sind 2 bis 5% der französischen Bevölkerung von Fibromyalgie betroffen, und in den USA leben rund 4 Millionen Erwachsene. Obwohl die Weltgesundheitsorganisation (WHO) Fibromyalgie als Krankheit im Jahr 1992 erkannt hat, ist dies noch nicht der Fall in Francia.Sin Aber zuerst Schriften zu diesem Syndrom wurden im achtzehnten Jahrhundert.

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