Fibromyalgi: En betennelse i hjernen demonstrert for første gang.

Den generelle betennelsen i hjernen hos pasienter med fibromyalgi har nettopp blitt identifisert. En reell fremgang i forhold til denne lille kjente og lite anerkjente sykdommen.

For første gang oppdaget forskerne en utbredt betennelse i hjernen hos pasienter med fibromyalgi  *  , en lite kjent tilstand. Hva å utvikle nye terapier Hans rapport ble publisert i tidsskriftet  Brain, Behavior and Immunity  . “Finne objektive nevrokemiske endringer i hjernen hos pasienter med fibromyalgi bør bidra til å redusere vedvarende stigma som mange pasienter står overfor. De blir ofte fortalt at deres symptomer er imaginære og at de ikke har noe, sier han. Marco Loggia, forskningsdirektør.

Diagnosen fibromyalgi forblir vanskelig å etablere

Kronisk smerte er det viktigste symptomet på fibromyalgi. Andre symptomer (tretthet, søvnforstyrrelser, hukommelsestap etc.) varierer fra en pasient til en annen og endres over tid. Til tross for identifisering av disse kliniske manifestasjonene, er diagnosen fibromyalgi fortsatt vanskelig å etablere. Hittil har ingen laboratorie- eller radiologisk undersøkelse vært i stand til å bekrefte dette. 

Vi analyserte 20 pasienter med fibromyalgi og 14 kontrollfrivillige i et første lag. Samtidig hadde en annen gruppe forskere dannet en kohorte på 11 pasienter og et like antall kontrolldeltakere. Forskerne sammenlignet sine data for å trekke felles konklusjoner.

Aktivering av glialceller i ulike områder av hjernen.

Til slutt var aktiveringen av glialceller i flere regioner i hjernen hos pasienter med fibromyalgi signifikant høyere enn hos kontrolldeltakere. I nervesystemet er glialceller cellene som danner miljøet til nevroner. “Aktiveringen av glialceller som vi observerte i studiene gir utløser inflammatoriske mediatorer som antas å føle smerteveiene og bidra til symptomer som tretthet,” konkluderer Marco Loggia. *

Fibromyalgi påvirker mellom 2 og 5% av den franske befolkningen, ifølge Fibromyalgie France-foreningen, og rundt 4 millioner voksne i USA. Selv om Verdens helseorganisasjon (WHO) anerkjente fibromyalgi som en sykdom i 1992, er dette fremdeles ikke tilfelle i Frankrike. Imidlertid ble de første skriftene om dette syndrom funnet i det attende århundre.

449 thoughts on “Fibromyalgi: En betennelse i hjernen demonstrert for første gang.

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