médicos geneticistas identificou 90 distúrbios de DNA pacientes, causando sintomas através de alterações no sistema nervoso e imunológico destes pacientes.
Eles têm muitas vezes se sentia incompreendido. Ou pior, acusado de simular uma doença. Mas agora a ciência comprova-los direito. E que os médicos geneticistas descobriram que a fibromialgia é uma doença de origem neurológica, resultado desequilíbrios neuroquímicos do sistema nervoso central.
Graças a um estudo realizado com 3.000 pessoas e dos quais dois terços deles estavam sofrendo de fadiga fibromialgia e cronicamente foi determinado que há 90 polimorfismos no DNA de pacientes que afetam o sistema imunológico e nervoso. Esta pesquisa “representa a única evidência de marcadores genéticos associados com fibromialgia”, dizem os autores, Genomic Genetics International (GGI).
“Não é evidência suficiente para considerar esta condição como uma doença de base orgânica, desde que seja diagnosticada corretamente , ” disse o Dr. José Ignacio Lao, diretor do GGI. O problema experimentado por pacientes que sofrem de esta condição é que o seu sistema imunológico tende a responder de uma forma exagerada .
Geneticistas descobriram a interação de dois genes que explicam por que o estímulo doloroso é mais forte em pacientes com fibromialgia. Existe ainda um outro gene receptor -chamado mu- opióide “que faz com que essas pessoas não percebem somente mais dor física, mas também a psíquica” exerce o diretor do GGI. “A rejeição social ou de um parceiro rompido deixa-los mais profundo do que as outras pessoas sem essa pegada variante genética”, acrescenta.
Além da dor sofrida pela fibromialgia – “em todos os níveis, não só músculo esquelético”, destaca estes capacidade Lao são afetados para manter o equilíbrio químico do cérebro.
Sofrem de um défice tendência de neurotransmissores-a substâncias químicas do cérebro responsável pela transmissão nervosa, portanto, dentro da patologia tem uma inclinação à perda de memória (comprometimento cognitivo precoce), depressão e transtornos do sono, falta serotonina. “Mesmo estressante para eles desencadear situações de surtos”, lembra o diretor do GGI.
O princípio da FIM DO ESTIGMA?
Embora fibromialgia foi identificado como uma doença pela Organização Mundial de Saúde (OMS) em 1992 -incluindo dentro de reumatismo na Classificação Internacional de doença-, muitas pessoas que sofrem com isso tiveram de suportar excessivamente duro estigma de ser simulando, em aos olhos dos outros, uma doença .
Embora hoje fibromialgia não tem remédio médico, é certo que há muitas esperanças no campo da biotecnologia para que ele possa encontrar uma solução definitiva. Genética é o desenvolvimento de novos agentes terapêuticos.
Você pode até fazer medicina preventiva em famílias com história. E em ambientes familiares onde há um caso de fibromialgia oito vezes a probabilidade de que mais casos aparecem, como mostram as estatísticas.
Em Espanha estima-se que 2,4% da população sofre de fibromialgia. Mesmo os casos ocorrem em crianças, mas poucos, que já aparece hipersensibilidade. Na verdade, muitas pessoas com a doença de velhos explicar que as crianças eram hipersensíveis a certos estímulos.
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