Alta taxa de síndrome de pernas inquietas em fibromialgia: estudo recente

Um estudo na edição de 15 de outubro do  Journal of Sleep Medicine Clínica  descobriu que adultos com fibromialgia apresentaram uma prevalência muito maior e risco de síndrome das pernas inquietas do que os controles saudáveis. O estudo sugere que RLS de tratamento podem melhorar o sono e qualidade de vida em pessoas com fibromialgia.

resultado de imagem

Os resultados mostram que a prevalência de síndrome das pernas inquietas foi cerca de 10 vezes maior no grupo fibromialgia (33 por cento) do que entre os controles (3,1 por cento). Após os ajustes estatísticos para fatores potenciais tais como a idade, o sexo e a etnia, os participantes com fibromialgia foram 11 vezes mais probabilidades do que os controlos de ter RLS (odds ratio = 11,2). Como esperado, considerável perturbação do sono foi relatada por participantes com fibromialgia usando o Índice de Pittsburgh qualidade do sono, insônia Índice de Gravidade e Escala de Sonolência Epworth. No grupo fibromialgia estes problemas de sono foram mais graves entre pessoas que também tinham RLS.

“Perturbação do sono é comum na fibromialgia, e muitas vezes difícil de tratar”, disse o autor contribuindo Dr. Nathaniel F. Watson, professor associado de neurologia na Universidade de Washington em Seattle, Wash. “Resulta do nosso estudo que uma parte substancial de dormir perturbação na fibromialgia é devido a síndrome das pernas inquietas “.

. A equipe de pesquisa liderada pelo Dr. Watson e principal autor Dr. Mari Viola-Saltzman da Loyola University Medical Center, em Maywood, Illinois, estudou 172 pessoas com fibromialgia que tinham uma idade média de 50 anos; 93 por cento eram do sexo feminino. Eles foram comparados com 63 controles saudáveis ​​que tinham uma idade média de 41 anos.

A fibromialgia foi identificado por auto-relato ou revisão dos prontuários, e foi confirmado no exame de acordo com as diretrizes publicadas com relação à presença de dor que é crônica e generalizada. A dor foi avaliada pelo relato subjectivo e objectivo por medição com um dolorímetro, um calibre de mola que é utilizado para aplicar taxas padronizadas de pressão de concurso pontos sobre os braços e as pernas.

De acordo com o National Institute of Arthritis e musculosqueléticas e Dermatopatias, fibromialgia pode causar dor significativa e fadiga. Estima-se que afeta 5 milhões de americanos idade de 18 anos ou mais, e entre 80 e 90 por cento das pessoas diagnosticadas com fibromialgia são mulheres. As causas da fibromialgia permanecem desconhecidos.

Síndrome das pernas inquietas foi diagnosticado através de um auto-administrados, questionário validado. RLS é uma desordem de movimento relacionadas com o sono que envolve uma necessidade de mover as pernas que é geralmente acompanhada por sensações causadas ou desconfortáveis ​​e desagradáveis ​​nas pernas. Este desejo começa ou piora durante períodos de descanso ou inatividade, é parcialmente ou totalmente resolvido pelo movimento, e piora ou só ocorre durante a noite. RLS ocorre 1,5 a duas vezes mais comum em mulheres do que em homens.

Watson observou que o tratamento da síndrome das pernas inquietas pode ser uma das chaves para reduzir a fadiga e melhorar a qualidade de vida em pessoas com fibromialgia. RLS pode muitas vezes ser tratados com sucesso com uma medicação, tais como pramipexol ou ropinirole.

“Desde síndrome das pernas inquietas é uma condição tratável, diagnóstico e tratamento da SPI em pacientes com fibromialgia tem o potencial de melhorar o seu sono”, disse Watson.

Segundo os autores, a natureza transversal do estudo não permitir o exame da causalidade. No entanto, vários aspectos das duas síndromes sugerem uma sobreposição lógica. Ambos os distúrbios envolvem anomalias sensoriais, e uma patofisiologia semelhante do sistema que regula o neurotransmissor dopamina tem sido proposta para ambas as síndromes. Além disso, a síndrome das pernas inquietas pode ser induzida por antidepressivos, que são um tratamento comum para a dor e depressão em fibromialgia. Além disso, o exercício foi mostrado para melhorar os sintomas de ambas as síndromes.

O estudo foi apoiado pelo Instituto Nacional de Artrite e musculosqueléticas e Dermatopatias dos Institutos Nacionais de Saúde e pela Associação Nacional de Pesquisa fibromialgia.

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