A ciência da cannabis desenvolve remendos para a dor nos pacientes com fibromialgia

A Cannabis Science, uma empresa especializada no desenvolvimento de terapias à base de cannabis, anunciou recentemente o desenvolvimento de duas novas drogas para alívio da dor em pessoas com fibromialgia e neuropatia diabética com dor no nervo.

Os dois novos analgésicos farmacêuticos serão comercializados como adesivos adesivos transdérmicos que administram uma certa dose de medicamento na corrente sanguínea por absorção através da pele do paciente.

As vias de administração de medicamentos transdérmicos têm o potencial de promover a cicatrização de uma área lesada do corpo. Este método de administração pode ser superior a outros tipos de administração de drogas, incluindo oral, tópica, intravenosa, intramuscular e outras, devido ao controle adicional sobre a dose administrada ao paciente.

O emplastro proporciona uma libertação mais controlada da medicação, quer utilizando uma membrana porosa para permitir que a medicação seja gradualmente absorvida através da pele, quer incorporando camadas finas da medicação no adesivo que funde com o calor corporal do paciente.

Os canabinóides têm uma ampla gama de aplicações medicinais, que remontam a milhares de anos. Atualmente, várias publicações científicas revisadas por pares documentam as vias bioquímicas subjacentes que modulam os canabinóides.

Esses adesivos contêm extrato de canabinóide de alta potência (CBD), o segundo maior cannabinoide da maconha após o THC (tetrahidrocanabinol). O extrato entra lentamente na corrente sanguínea e depois entra no sistema nervoso central do paciente para atuar como analgésico.

O CBD tem propriedades antiinflamatórias e analgésicas sem efeitos psicoativos conhecidos. A pesquisa mostrou que o CBD pode ser um tratamento eficaz para muitos tipos de dor, particularmente a dor inflamatória. Alguns estudos também mostraram que o CBD pode superar a medicação tradicional no tratamento da dor inflamatória.

“Enquanto nos esforçamos para aumentar a capacidade de crescimento de nossa terra e as instalações para produzir nosso próprio produto para fornecer a nossos cientistas materiais patenteados para fazer essas formulações, também estamos ocupados investigando mais necessidades potenciais de aplicações médicas relacionadas à Cannabis e desenvolvendo os métodos para entregar esses medicamentos ”, disse Raymond C. Dabney, CEO da Cannabis Science em um comunicado de imprensa.

“Como mais estados em todo o país [nos EUA] UU.] Legislação para a legalização de cannabis e drogas derivadas da cannabis, aqui na Cannabis Science estamos focados no desenvolvimento de formulações e aplicações farmacêuticas para suprir a enorme demanda crescente que se espera anos ”, afirmou Dabney.

Estima-se que a fibromialgia acometa de 2% a 8% da população. Pacientes com fibromialgia apresentam dor crônica generalizada e maior resposta à dor sob pressão.

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