“Los desencadenantes de la fibromialgia”

Este resumen informativo de la fibromialgia es un método para diseminar la fibromialgia basado en la investigación y la práctica del Dr. med. Manuel Martínez Lavín, un mexicano, uno de los mayores expertos en fibromialgia.

El tema general es la patogenia o la causa del desarrollo de la fibromialgia, d. H. Los mecanismos o factores que conducen a la fibromialgia, tanto genéticamente como ambientalmente condicionados y forman el desarrollo de la enfermedad.

S Dr. Dr. Manuel Martinez Lavin ataca la fibromialgia que conduce al síndrome de dolor neuropático debido a la hiperactividad simpática. Dado que esto es en la fibromialgia, se discute una afección asociada con la VSG sobre cómo puede estar el centro nervioso en la patogénesis: la forma en que la pobreza se puede convertir en dolor crónico.

Predisposición genética

Resultado de la imagen para la genética.

Para el doctor Manuel Martínez Lavín tiene una predisposición genética para el desarrollo de la fibromialgia. Los familiares inmediatos de los afectados tienen ocho veces más probabilidades de desarrollar la enfermedad que la población general. Los estudios en sujetos gemelos sugieren que aproximadamente el 50% de los factores que causan la fibromialgia son hereditarios y la otra mitad del medio ambiente.

Varios grupos de investigación se han centrado en el estudio de las variaciones genéticas asociadas con la respuesta al sistema de estrés. La mayoría de los estudios fueron positivos. Los pacientes con fibromialgia, diferentes polimorfismos del gen de la catecol-o-metiltransferasa y la serotonina, están asociados con una enzima, y ​​la capacidad de descomponer las catecolaminas (adrenalina) y los receptores adrenérgicos disfuncionales es insuficiente.

factores ambientales

Resultado de imagen para whiplash

El estudio de la cohorte de individuos que nació en 1958 en las Islas Británicas, capaz de definir en el futuro diversos eventos en el curso de la vida de las personas, puede ser el factor de riesgo para el desarrollo posterior de un dolor crónico generalizado. Estas situaciones son: los efectos secundarios en la infancia, como los conflictos familiares, la muerte del padre o la madre, las limitaciones económicas o la falta de socialización en los años escolares. Esto también sugiere que un estilo de vida loco es otro factor de riesgo para desarrollar estos tipos de síntomas. La ingesta de grasa, la obesidad, la falta de ejercicio y fumar aumentan el riesgo de dolor crónico.

La lesión física, especialmente los accidentes automovilísticos con latigazo cervical en la columna cervical, es otro evento de fibromialgia. También los diversos traumas emocionales, incluyendo el abuso sexual, la intimidación en el trabajo, el divorcio o la muerte de un ser querido. Luchadores de diferentes guerras desarrollan síndromes similares a los de la fibromialgia.

Varios agentes infecciosos pueden promover el desarrollo de la fibromialgia.

Estrés y sufrimiento

Segun el Dr. Martínez Lavín, está claro que el desarrollo de la fibromialgia está relacionado con factores de estrés físico, infeccioso o emocional. Para él, el estrés es “todo estímulo, físico o emocional, que trata de contrarrestar la homeostasis”. El sufrimiento de Selye es la respuesta mal adaptada al estrés que causa daño físico y / o emocional. m La 
fibromialgia a menudo causa síntomas. El miedo y la depresión son dos manifestaciones comunes. Las personas que sufren de fibromialgia a menudo tienen una personalidad rígida y perfeccionista. Obsesionados en el cumplimiento de sus deberes dentro y fuera de la casa, se crían para cuidar de sus seres queridos.

Doctora Martínez Lavín, los cambios en el líquido cefalorraquídeo, especialmente Vaeroy, describió el aumento de las concentraciones de sustancia P (euro transmisor de dolor primario) en pacientes con fibromialgia. En imágenes funcionales, el grupo de Mountz encontró que los pacientes con fibromialgia redujeron el flujo de sangre en el tálamo y el núcleo caudado. El tálamo es un centro para el procesamiento del dolor y la función autónoma. El grupo de Gracelys presionó el pulgar de los pacientes con fibromialgia hasta que ella causó mucho dolor. La presión promedio de 2.4 kg / cm2 fue suficientemente saludable en comparación con 4.2 kg / cm2. La realización de la IRMf mientras se sentía un dolor intenso ocurrió tanto en pacientes como en áreas de control de control del cerebro,

insomnio

Resultado de la imagen para el insomnio.

Los estudios electroencefalográficos de Moldofsky et al demostraron que los pacientes con fibromialgia en condiciones de sueño profundo penetraron las ondas alfa e incluso desarrollaron dolor difuso y alodinia. Estudios recientes han demostrado que las personas con fibromialgia tienen un aumento en los episodios de excitación y despertar.

Resonanzphänomen (“Wind-up”)

Resultado de la imagen para los puntos sensibles de la fibromialgia

El grupo del Dr. Staud ha demostrado que existe un fenómeno de resonancia en personas con fibromialgia para los estímulos dolorosos, que demuestra la sensibilización del sistema somatosensorial.

Al final

Resultado de la imagen para la fibromialgia

Para el doctor Martínez Lavín, la fibromialgia es un síndrome de dolor neuropático que se apoya en una hiperactividad simpática basada en los siguientes tres argumentos: 
– La presencia de dolor crónico sin dañar la estructura corporal. 
– La presencia de alodinia como manifestación fundamental de la fibromialgia. 
– La presencia de parestesias como síntomas que distinguen la condición.

Sugiere que la fibromialgia es un síndrome que se mantiene mediante una hiperactividad simpática basada en los siguientes tres argumentos: 
– Su frecuente aparición postraumática. 
– Datos de la incesante dominación simpática. 
– El estudio doble ciego demostró que las personas tienen dolor de fibromialgia inducido por inyección de norepinefrina (adrenalina).

Otra contribución del Dr. Martínez Lavín sobre la etiopatogenia de la fibromialgia es cómo la ansiedad puede convertirse en dolor crónico. La disautonomía de la fibromialgia resume los principales hallazgos patogénicos descritos por otros grupos de investigación en una explicación detallada. La disautonomía es una explicación clara para los trastornos del sueño y la fatiga crónica.

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96 thoughts on ““Los desencadenantes de la fibromialgia”

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