SYNDROME DOULOUREUX RÉGIONAL COMPLEXE (CRPS) ET FIBROMYALGIE

IL Y A QUELQUES ANNÉES, PAIGE HOWITT EST ENTRÉ DANS UNE OPÉRATION DE ROUTINE POUR SON GENOU. PEU DE TEMPS APRÈS, ELLE A COMMENCÉ À RESSENTIR UNE DOULEUR INTENSE RAYONNANT À PARTIR DU SITE DE LA CHIRURGIE. COMME LES SEMAINES PASSAIENT, LA DOULEUR A COMMENCÉ À SE RÉPANDRE ET SE DÉVELOPPER PLUS INTENSE. MÊME SI ELLE NE LE SAVAIT PAS À L’ÉPOQUE, ELLE SOUFFRAIT D’UNE MALADIE APPELÉE « SYNDROME DE LA DOULEUR RÉGIONALE COMPLEXE (CRPS). »

SDRC est une maladie rare qui peut affecter les personnes qui ont récemment subi un traumatisme au corps. Dans le cas de Paige, il était la chirurgie. Mais SDRC peut aussi affecter les personnes qui ont eu des accidents vasculaires cérébraux, crises cardiaques ou des blessures graves. Nous ne savons pas avec certitude ce qui cause des gens comme Paige à développer SDRC, mais la réponse se trouve probablement dans le système nerveux.

Les nerfs sont évidemment très sensibles. Et quand ils sont exposés à un traumatisme, ils deviennent parfois hyperactif, envoyer des signaux de douleur au cerveau qui sont beaucoup plus intenses que la lésion initiale et peut continuer à le faire si longtemps après la blessure est guérie. Pensez-y comme un cadran qui contrôle la douleur étant retournée et se coincé là-bas. En conséquence, les gens comme Paige traitent, la douleur angoissante constante.

Et comme Paige, les gens avec SDRC trouvent souvent que la douleur commence à contrôler tous les aspects de leur vie. Paige foundthat la douleur était si intense qu’elle a dû réduire ses heures de travail et ne peut plus faire le genre de choses qu’elle avait l’habitude de profiter. Et parce que la chaleur rend sa douleur pire, elle ne peut jamais être loin d’un sac de glace.

De toute évidence, l’histoire de Paige est familier à tous ceux qui souffre de la maladie. Mais il est aussi familier à tous ceux qui souffre de fibromyalgie. Après tout, quelqu’un qui a Fibromyalgie sait comment la douleur chronique peut complètement changer la vie de quelqu’un. Et la similitude entre les deux conditions a conduit certaines personnes à spéculer qu’il pourrait y avoir un lien entre CRPS et la fibromyalgie. Mais est-il quelque chose à cette théorie? Jetons un coup d’oeil à certains éléments de preuve.

CRPS et Fibromyalgie

Il y a des similitudes évidentes entre CRPS et Fibromyalgie. Les deux causent la douleur sans source évidente. Les deux conditions peuvent se développer après un traumatisme physique. Et à chaque condition, la douleur peut être suffisamment grave pour être invalidante. Les personnes ayant soit CRPS et la fibromyalgie ont souvent des difficultés à bouger, et les sites où la douleur est localisée sont généralement sensibles au toucher. Et les changements de température peuvent aggraver les conditions.

Mais il y a quelques différences importantes aussi bien. Dans les cas de SDRC, la douleur est habituellement situé sur le site de la blessure. Dans le cas de Paige, la douleur se concentre sur le genou. C’est différent de la fibromyalgie, où la douleur se propage à travers presque tout le corps, en particulier dans les 18 points spécifiques. En outre, SDRC conduit souvent à un gonflement autour du site de la lésion initiale. Et tandis que les personnes atteintes de fibromyalgie peuvent avoir un gonflement, il est généralement pas aussi localisée que dans SDRC.

Mais malgré les différences, il peut y avoir un lien important entre les deux conditions. Comme avec SDRC, la douleur de la fibromyalgie est probablement enracinée dans le système nerveux. Des chercheurs australiens ont récemment proposeda explication possible pour les deux conditions qui pourraient expliquer cet égard.

Pour l’essentiel, l’idée est que l’inflammation dans le système nerveux provoque les nerfs pour transmettre des signaux de douleur au cerveau. Une fois que les cellules nerveuses sont endommagées, le système immunitaire commence à envoyer des cellules aux nerfs pour les réparer. Comme les cellules nerveuses guérissent, ils deviennent plus sensibles en réponse à ces cellules immunitaires. Voilà pourquoi les blessures peuvent sembler pousser plus douloureux des heures supplémentaires avant la guérison.

Habituellement, les cellules nerveuses cessent d’être finalement plus sensible et la douleur disparaît. Mais dans les cas de SDRC et la fibromyalgie, les cellules nerveuses peuvent se coincer dans la phase d’hypersensibilité. Le système immunitaire continue d’envoyer des cellules des nerfs et le déclenchement de la réponse à la douleur.

Certaines de ces cellules immunitaires sont appelées microglies, et d’autres chercheurs ont suggéré que la microglie pourrait effectivement être la clé pour comprendre la fibromyalgie. En fait, ils sont des cellules immunitaires qui traversent la barrière entre le sang et le cerveau. Comme ils se déplacent à travers le corps, le corps microglies déclencher à libérer des substances chimiques qui causent l’inflammation, ce qui peut créer un cycle où les nerfs sont constamment enflammées.

Il est possible que les deux CRPS et la fibromyalgie sont causés par cette interaction entre le système immunitaire et les nerfs. En étudiant CRPS et d’autres affections du système nerveux, nous pouvons être en mesure d’en apprendre davantage sur la fibromyalgie. Et finalement, cela peut conduire à une guérison.

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